Summary

Alpha-helices can be stabilized by positively-charged residues in the final turn (1).

Figure

Ref (1)

1.
Ferrari ÁJR, Dixit SM, Thibeault J, Garcia M, Houliston S, Ludwig RW, et al. Large-scale discovery, analysis and design of protein energy landscapes. Nature. 2026;654(8120):1108–18. Available from: https://doi.org/10.1038/s41586-026-10465-z