Summary
High predicted aligned error values correlate with greater likelihood of violating experimental distance measurements (from crosslinking) (1).
Figures
Ref (1)
1.
McCafferty CL, Pennington EL, Papoulas O, Taylor DW, Marcotte EM. Does AlphaFold2 model proteins’ intracellular conformations? An experimental test using cross-linking mass spectrometry of endogenous ciliary proteins. Communications Biology. 2023;6(1). Available from: https://doi.org/10.1038/s42003-023-04773-7