Summary
Inverse folding can be improved by incorporating larger PLMs (1). This was shown using CarbonDesign, which incorporates an ESM during inference.
Figures
Figure 2d from (1)
1.
Ren M, Yu C, Bu D, Zhang H. Accurate and robust protein sequence design with CarbonDesign. Nature Machine Intelligence. 2024;6(5):536–47. Available from: https://doi.org/10.1038/s42256-024-00838-2