Ligand-binding sites fit experimental electron density better than other parts of protein structures

Summary

Experimental structure of proteins collected using cryo-EM and X-ray-crystallography are higher-quality in ligand-binding areas than other areas (1).

Figures

Ref (1)

1.

Wankowicz SA. Modeling Bias Toward Binding Sites in PDB Structural Models. openRxiv; 2024. Available from: https://doi.org/10.1101/2024.12.14.628518