Summary
About ~60% of proteins from viral genomes are structurally distinct from those found in eukaryotic genomes (1). This was determined using structures predicted with AlphaFold2 and Foldseek.
1.
Nomburg J, Doherty EE, Price N, Bellieny-Rabelo D, Zhu YK, Doudna JA. Birth of protein folds and functions in the virome. Nature. 2024;633(8030):710–7. Available from: https://doi.org/10.1038/s41586-024-07809-y