Summary
Learning to predict TM-scores from sequence alone (by learning cosine similarity from whole-sequence representations), allows PLMs to learn structural classifications (1).
Figures
Figure 2 from (1)
1.
Hamamsy T, Morton JT, Blackwell R, Berenberg D, Carriero N, Gligorijevic V, et al. Protein remote homology detection and structural alignment using deep learning. Nature Biotechnology. 2023;42(6):975–85. Available from: https://doi.org/10.1038/s41587-023-01917-2