Summary
pTM is less lenient than pLDDT when assessing structurally novel alternate conformations (1).
See also
1.
Schwartz AC, Stein RA, Gil-Iturbe E, Quick M, Mchaourab HS. Alternating Access of a Neurotransmitter:Sodium Symporter Bacterial Homolog Determined from AlphaFold2 Ensembles and DEER Spectroscopy. openRxiv; 2024. Available from: https://doi.org/10.1101/2024.04.08.587957