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All atom structure prediction of RNA is driven by memorization

All-atom structure prediction of RNA is driven by memorization

Created May 05, 2025Modified Apr 21, 2026

  • structure-prediction/limitations

Summary

All-atom protein structure prediction of RNA and protein-RNA complexes is driven by memorization (1).

Figures

Ref (1)

See also

  • Protein-ligand co-folding methods do not generalize beyond their training set
1.
Ludaic M, Elofsson A. Limits of deep-learning-based RNA prediction methods. openRxiv; 2025. Available from: https://doi.org/10.1101/2025.04.30.651414

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Backlinks

  • Correct antibody-antigen prediction in AF3 and related models is partially determined by training set similarity
  • Memorization in protein structure prediction
  • Protein-ligand co-folding methods do not generalize beyond their training set

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