Summary
Enzymes generated by Ancestral sequence reconstruction tend to have greater expression (1).
1.
Johnson SR, Fu X, Viknander S, Goldin C, Monaco S, Zelezniak A, et al. Computational scoring and experimental evaluation of enzymes generated by neural networks. Nature Biotechnology. 2024;43(3):396–405. Available from: https://doi.org/10.1038/s41587-024-02214-2