Antibody language models are able to distinguish correctly and incorrectly paired sequences, but are sensitive to scale and training dataset size

Summary

Antibody-specific protein language models are able to distinguish correctly and incorrectly paired sequences, but are sensitive to model scale and training dataset size (1).

Figures

Ref (1)

See also

• Paired antibody LMs outperform equivalent unpaired LMs on sequence recovery for various regions

1.

Neyestanak MS, Burbach SM, Ng K, Gangavarapu P, Hurtado J, Magura J, et al. Data-optimal scaling of paired antibody language models. openRxiv; 2025. Available from: https://doi.org/10.1101/2025.09.02.673765