Summary
Broadly neutralizing antibodies against HIV evolve in only a small number of patients, and usually in low titers (1).
1.
Ovchinnikov V, Louveau JE, Barton JP, Karplus M, Chakraborty AK. Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies. eLife. 2018;7. Available from: https://doi.org/10.7554/elife.33038