Quartz 4

Buried nonpolar surface area is a major determinant of whether de novo designed proteins are stable

Created Modified

Summary

Buried nonpolar surface area is a major determinant of whether designed proteins are stable (1,2).

Figures

Ref (1)

1.
Rocklin GJ, Chidyausiku TM, Goreshnik I, Ford A, Houliston S, Lemak A, et al. Global analysis of protein folding using massively parallel design, synthesis, and testing. Science. 2017;357(6347):168–75. Available from: https://doi.org/10.1126/science.aan0693
2.
Ferrari ÁJR, Dixit SM, Thibeault J, Garcia M, Houliston S, Ludwig RW, et al. Large-scale discovery, analysis, and design of protein energy landscapes. openRxiv; 2025. Available from: https://doi.org/10.1101/2025.03.20.644235

Graph View