Summary

An evolutionary pathway between two folds in FixJ and KdpE is proposed using Ancestral sequence reconstruction and (AlphaFold2) modeling (1).

Figures

Ref (1)

1.
Chakravarty D, Sreenivasan S, Swint-Kruse L, Porter LL. Identification of a covert evolutionary pathway between two protein folds. Nature Communications. 2023;14(1). Available from: https://doi.org/10.1038/s41467-023-38519-0