Summary
Individual V gene, D gene, and J gene usage is highly uneven and nonrandom (1,2).
Figures
Ref (2)
1.
Rees AR. Understanding the human antibody repertoire. mAbs. 2020;12(1). Available from: https://doi.org/10.1080/19420862.2020.1729683
2.
Hong B, Wu Y, Li W, Wang X, Wen Y, Jiang S, et al. In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires. Frontiers in Immunology. 2018;9. Available from: https://doi.org/10.3389/fimmu.2018.00128