Kappa subtype restricts CDRH3 dynamics

Summary

The light chain kappa subtype is more likely to restrict CDRH3 dynamics (Guloglu and (1)).

See also

• Loops from one V-region chain affect the conformations and dynamics of loops in the other chain

1.

Guloglu B, Deane CM. Specific attributes of the VL domain influence both the structure and structural variability of CDR-H3 through steric effects. Frontiers in Immunology. 2023;14. Available from: https://doi.org/10.3389/fimmu.2023.1223802