Summary
Most protein complexes, be they homo- or heterooligomers, are symmetric (1). This is consistent with their mass prediction of homo-oligomers using AlphaFold2.
1.
Schweke H, Pacesa M, Levin T, Goverde CA, Kumar P, Duhoo Y, et al. An atlas of protein homo-oligomerization across domains of life. Cell. 2024;187(4):999-1010.e15. Available from: https://doi.org/10.1016/j.cell.2024.01.022