Summary
FR2 is more hydrophilic in nanobodies than in antibodies (1).
Figures
Ref (1)
1.
Ketaren NE, Fridy PC, Malashkevich V, Sanyal T, Brillantes M, Thompson MK, et al. Unique Binding and Stabilization Mechanisms Employed By and Engineered Into Nanobodies. openRxiv; 2023. Available from: https://doi.org/10.1101/2023.10.22.563475