Summary
Affinity maturation of de novo designed minibinders introduces mutations far from the active site (1).
References
1.
Alcantar MA, Paulk AM, Moradi S, Bhar D, Keller GLJ, Sanyal T, et al. Mapping the evolution of computationally designed protein binders. openRxiv; 2025. Available from: https://doi.org/10.1101/2025.10.04.680454