Summary
The orientation between the heavy and light chains of antibodies can affect the conformation of CDRH3 (1).
1.
Fernández-Quintero ML, Kokot J, Waibl F, Fischer A-LM, Quoika PK, Deane CM, et al. Challenges in antibody structure prediction. mAbs. 2023;15(1). Available from: https://doi.org/10.1080/19420862.2023.2175319