Nanobodies are more easily expressed in bacteria and yeast than IgG antibodies

Summary

Nanobodies are more easily expressed than IgG antibodies or scFvs in platforms involving yeast and E. coli (1).

1.

Rossotti MA, Bélanger K, Henry KA, Tanha J. Immunogenicity and humanization of single‐domain antibodies. The FEBS Journal. 2021;289(14):4304–27. Available from: https://doi.org/10.1111/febs.15809