Protein engineering refers to the modification of proteins to have specific properties. This can range in magnitude from the introduction of mutations to entire domains.
Engineered domains
- BRIL (used to bulk of proteins for cryo-EM)
- ALFA-tag (used to bulk of proteins for cryo-EM)
- Heterodimerization domains (used to stabilize transient dimers)
- Engineered trimerization domains (used to stabilize transient trimers, particularly for trimeric viral fusion proteins)