Display methods are a set of high-throughput methods for protein engineering in which large numbers of recombinant protein variants are synthesized by phages and tested for binding. It’s commonly used to design antibodies or protein binders. There are numerous variations of this method.
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Chan DTY, Groves MAT. Affinity maturation: highlights in the application of in vitro strategies for the directed evolution of antibodies. Emerging Topics in Life Sciences. 2021;5(5):601–8. Available from: https://doi.org/10.1042/etls20200331