Partial diffusion of de novo designed binders and VHHs improves refoldability and designability scores

Summary

Partial diffusion and flow matching of de novo binders binders and VHHs improves refoldability and designability (1).

Figures

Figures from (1); binders and VHHs on top and bottom

See also

• De novo antibody design

1.

Yu Q, Guo L, Qin X, Huang X, Tian B, Wang H, et al. High-Affinity Protein Binder Design via Flow Matching and In Silico Maturation. openRxiv; 2026. Available from: https://doi.org/10.64898/2026.01.19.700484