Summary
Somatic hypermutation of antibodies correlates with lower hydrophobicity (1).
Figures
Figure 2B from (1)
See also
- Antibody hydrophobicity sometimes correlates with polyreactivity
- Antibody thermostability is not correlated with hydrophobicity
- Somatic hypermutation correlates with lower polyreactivity
1.
Shehata L, Maurer DP, Wec AZ, Lilov A, Champney E, Sun T, et al. Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability. Cell Reports. 2019;28(13):3300-3308.e4. Available from: https://doi.org/10.1016/j.celrep.2019.08.056