Quartz 4
Search
Search
Dark mode
Light mode
Explorer
Tag: cdrh3
13 items with this tag.
May 06, 2026
CDR sequence changes are enough to destabilize antibodies
cdrh3
May 06, 2026
CDR1 and CDR2 contribute more to antibody stability than CDR3
cdrh3
protein-folding/unfolding
Apr 21, 2026
CDR3 far more likely to be part of paratope of nanobodies compared to antibodies
cdrh3
antibody-antigen-interactions/misc
Apr 21, 2026
CDR3 loops encode specificity while CDR1 and CDR2 encode cross-reactivity
antibody-developability/polyspecificity
cdrh3
antibody-antigen-interactions/misc
Apr 21, 2026
CDRH3 conformational rigidity reduces cross reactivity
cdrh3
antibody-developability/polyspecificity
antibody-antigen-interactions/misc
Apr 21, 2026
CDRH3 has most contacts with antigen
cdrh3
protein-protein-interactions
antibody-antigen-interactions/misc
Apr 21, 2026
CDRH3 is necessary but insufficient to guarantee binding to a particular epitope
cdrh3
antibody-antigen-interactions/misc
Apr 21, 2026
Conformational entropy in antibodies is inversely proportional to antigen affinity
cdrh3
protein-protein-interactions
antibody-antigen-interactions/binding-affinity
Apr 21, 2026
CDR3 mediates heavy-light chain pairing preferences by making contacts to framework residues
cdrh3
antibody-framework
Apr 21, 2026
CDRH3 is shorter in mice and therapeutic Abs
cdrh3
Apr 21, 2026
DL structure prediction methods cannot predict CDR conformations unseen during training
cdrh3
structure-prediction/limitations
antibodies/engineering-and-design
Apr 21, 2026
Light chain coherence
light-chains
cdrh3
Apr 21, 2026
Simultaneous design of scFv loops predicted to lead to more fit sequences
cdrh3
antibodies/engineering-and-design